A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20973 |
| Swiss-prot Accession number | O42329 (Sequence in FASTA format) |
| Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
| Source organism | Clarias gariepinus (Sharptooth catfish) (African catfish) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Clariidae; Clarias. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
| Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Length | 379 Amino acids |
| Molecular weight | 42771 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 9030732 2 Bogerd J.; Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P43306 Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |