A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21646 |
| Swiss-prot Accession number | P43088 (Sequence in FASTA format) |
| Description | Prostaglandin F2-alpha receptor;PGF2 alpha receptor;Alternative Name: Prostanoid FP receptor;Alternative Name: PGF receptor |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). |
| Protein Length | 359 Amino acids |
| Molecular weight | 40055 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8300593 2 PubMed abstract 9341156 3 PubMed abstract 14702039 4 PubMed abstract 16710414 5 PubMed abstract 15489334 |
| Hormone | Detail in HMRbase |
| Gene ID | 5737 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |