A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21643 |
| Swiss-prot Accession number | P43116 (Sequence in FASTA format) |
| Description | Prostaglandin E2 receptor EP2 subtype;Alternative Name: Prostanoid EP2 receptor;Alternative Name: PGE receptor, EP2 subtype |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Placenta and lung. |
| Post translational modification | N/A |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. |
| Protein Length | 358 Amino acids |
| Molecular weight | 39761 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8078484 2 PubMed abstract 10521663 3 PubMed abstract 15489334 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 5732 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |