| HMRbase accession number | 21634 |
| Swiss-prot Accession number | Q8TDS5 (Sequence in FASTA format) |
| Description | Oxoeicosanoid receptor 1;Alternative Name: 5-oxo-ETE G-protein coupled receptor;Alternative Name: G-protein coupled receptor TG1019;Alternative Name: G-protein coupled receptor 170;Alternative Name: G-protein coupled receptor R527 |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. |
| Post translational modification | N/A |
| Function | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. |
| Protein Length | 423 Amino acids |
| Molecular weight | 45811 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 12065583
2 PubMed abstract 12606753
3 PubMed abstract 12044878
4 PubMed abstract 15815621
5 PubMed abstract 15489334
|
| Hormone | Detail in HMRbase
Detail in HMRbase
|
| Gene ID | 165140 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | |
A database of hormones and their receptors