A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21499 |
| Swiss-prot Accession number | P20153 (Sequence in FASTA format) |
| Description | Protein ultraspiracle;Alternative Name: XR2C;Alternative Name: Chorion factor 1;Alternative Name: Nuclear receptor subfamily 2 group B member 4 |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for ecdysone. May be an important modulator of insect metamorphosis. Plays an important part in embryonic and post-embryonic development. Binds to ecdysone response elements (ECRES) such as in the promoter region of s15 chorion gene. |
| Protein Length | 508 Amino acids |
| Molecular weight | 55244 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 2169594 2 PubMed abstract 2165589 3 PubMed abstract 10731132 4 PubMed abstract 12537572 5 PubMed abstract 10731137 6 PubMed abstract 12537569 7 PubMed abstract 2120114 8 PubMed abstract 8247157 9 PubMed abstract 18327897 |
| Hormone | N/A |
| Gene ID | 31165 |
| PDB ID | 1HG4 1R0O 2HAN |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |