| HMRbase accession number | 21484 |
| Swiss-prot Accession number | Q90416 (Sequence in FASTA format) |
| Description | Retinoic acid receptor RXR-gamma-A;Alternative Name: Retinoid X receptor gamma-A;Alternative Name: Retinoic acid receptor RXR-alpha;Alternative Name: Retinoid X receptor alpha;Alternative Name: Nuclear receptor subfamily 2 group B member 3-A |
| Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Nucleus |
| Developmental Stage | Expressed both maternally and zygotically. |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Uniformly expressed from the blastula to mid- gastrula stages. In late gastrula stages, there is specific expression in the presumptive hindbrain and spinal cord. At 16 hours post-fertilization (hpf), expressed in the hindbrain from rhombomere 7/8 to the anterior spinal cord; this expression continues until 42 hpf. At 24 hpf, also expressed in the lateral plate mesoderm flanking rhombomere 6 and in the cranial neural crest, but not in the migrating crest. At 26 hpf, also expressed in retina. At 48 hpf, strong retinal expression. |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). Activates transcription of target genes via binding to an RXR response element. |
| Protein Length | 441 Amino acids |
| Molecular weight | 48720 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7565671
2 PubMed abstract 16448862
3 PubMed abstract 17195188
|
| Hormone | N/A |
| Gene ID | 30464 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
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