A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21473 |
| Swiss-prot Accession number | Q90415 (Sequence in FASTA format) |
| Description | Retinoic acid receptor RXR-alpha-B;Alternative Name: Retinoid X receptor alpha-B;Alternative Name: Nuclear receptor subfamily 2 group B member 1-B |
| Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Nucleus |
| Developmental Stage | Expressed both maternally and zygotically. |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Uniform expression from the blastula to mid- gastrula stages. At 12 hours post-fertilization (hpf), expressed strongly in the tail and weakly elsewhere. At 24 hpf, weak expression in the forebrain, eyes and pharyngeal endoderm and continued expression in the tail mesoderm. At 48 hpf, anterior expression limited to ventral cells underlying the head, medial expression in the pectoral fin bud mesoderm and continued tail expression. |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). |
| Protein Length | 379 Amino acids |
| Molecular weight | 42556 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7565671 2 PubMed abstract 16448862 3 PubMed abstract 17195188 |
| Hormone | N/A |
| Gene ID | 793011 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |