A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21463 |
| Swiss-prot Accession number | P28699 (Sequence in FASTA format) |
| Description | Retinoic acid receptor gamma;RAR-gamma;Alternative Name: Nuclear receptor subfamily 1 group B member 3 |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Nucleus |
| Developmental Stage | It is synthesized during oogenesis and persists during early cleavage. It accumulates at gastrulation (stage 10), peaks in quantity during neurulation (stage 17), then drops to a low level after stage 26. |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression. |
| Protein Length | 476 Amino acids |
| Molecular weight | 53034 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 1312717 2 PubMed abstract 1846602 3 PubMed abstract 8641047 |
| Hormone | N/A |
| Gene ID | 397983 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |