A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21435 |
| Swiss-prot Accession number | Q9GLW0 (Sequence in FASTA format) |
| Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
| Source organism | Canis familiaris (Dog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular location | Nucleus. Note=Diverse nuclear localization patterns of PR observed in tumorous mammary and uterine tissue, including strong nuclear or perinuclear localization, heterogeneous expression or complete lack of expression, depending on tumor type and stage |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in mammary gland and uterus. |
| Post translational modification | N/A |
| Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
| Protein Length | 939 Amino acids |
| Molecular weight | 98418 |
| Domain Name | Hormone_recep Prog_receptor zf-C4 |
| References | 1 PubMed abstract 11282275 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 403621 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |