A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21411 |
| Swiss-prot Accession number | Q15406 (Sequence in FASTA format) |
| Description | Nuclear receptor subfamily 6 group A member 1;Alternative Name: Germ cell nuclear factor;GCNF;hGCNF;Alternative Name: Retinoid receptor-related testis-specific receptor;RTR;hRTR |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR6 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Shows highest expression in the germ cells of the adult testis. |
| Post translational modification | N/A |
| Function | Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity). |
| Protein Length | 480 Amino acids |
| Molecular weight | 54383 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 8982251 2 PubMed abstract 9177477 3 PubMed abstract 9134503 4 PubMed abstract 9537518 5 PubMed abstract 9493564 6 PubMed abstract 15164053 7 PubMed abstract 15489334 8 PubMed abstract 12080054 |
| Hormone | N/A |
| Gene ID | 2649 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |