A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21348 |
| Swiss-prot Accession number | P97947 (Sequence in FASTA format) |
| Description | RecName: Nuclear receptor subfamily 0 group B member 2;Alternative Name: Orphan nuclear receptor SHP;Alternative Name: Small heterodimer partner; |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. |
| Tissue Specificity | Detected in kidney, testis, heart and liver. |
| Post translational modification | N/A |
| Function | Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. |
| Protein Length | 260 Amino acids |
| Molecular weight | 28750 |
| Domain Name | Hormone_recep |
| References | 1 PubMed abstract 9003453 2 PubMed abstract 15489334 3 PubMed abstract 15721253 4 PubMed abstract 15976031 |
| Hormone | N/A |
| Gene ID | 117274 |
| PDB ID | 1YP0 1ZGY 1ZH7 |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |