A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21244 |
| Swiss-prot Accession number | Q5QJV7 (Sequence in FASTA format) |
| Description | RecName: Steroid hormone receptor ERR1;Alternative Name: Estrogen-related receptor, alpha;ERR-alpha;Alternative Name: Nuclear receptor subfamily 3 group B member 1; |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Nucleus (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | Phosphorylated (Probable). |
| Function | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus (By similarity). |
| Protein Length | 422 Amino acids |
| Molecular weight | 45464 |
| Domain Name | zf-C4 |
| References | 1 PubMed abstract 15489334 |
| Hormone | N/A |
| Gene ID | 293701 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |