A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21206 |
| Swiss-prot Accession number | P16376 (Sequence in FASTA format) |
| Description | RecName: Steroid receptor seven-up, isoform A;Alternative Name: Nuclear receptor subfamily 2 group F member 3, isoform A; |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in several embryonic tissues; dorsal vessel, oenocyte and fat body. CNS expression is dynamic and confined to temporally restricted subsections of the NB lineage; expressed in many NB and GMCs, but only a small number of neurons. |
| Post translational modification | N/A |
| Function | Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC-2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs). |
| Protein Length | 746 Amino acids |
| Molecular weight | 76814 |
| Domain Name | Hormone_recep zf-C4 zf-C4_C |
| References | 1 PubMed abstract 2105166 2 PubMed abstract 10731132 3 PubMed abstract 12537572 4 PubMed abstract 15691762 |
| Hormone | N/A |
| Gene ID | 41491 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |