A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21083 |
| Swiss-prot Accession number | Q28596 (Sequence in FASTA format) |
| Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
| Source organism | Ovis aries (Sheep) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
| Protein Length | 398 Amino acids |
| Molecular weight | 45089 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 9048604 |
| Hormone | P62969 Detail in HMRbase |
| Gene ID | 443425 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |