A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21070 |
| Swiss-prot Accession number | Q02644 (Sequence in FASTA format) |
| Description | Growth hormone-releasing hormone receptor precursor (GHRH receptor)(GRF receptor) (GRFR). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | Pituitary gland. |
| Post translational modification | N/A |
| Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
| Protein Length | 464 Amino acids |
| Molecular weight | 51522 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 1333056 2 PubMed abstract 1334535 |
| Hormone | P09916 Detail in HMRbase |
| Gene ID | 25321 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |