A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21067 |
| Swiss-prot Accession number | Q01776 (Sequence in FASTA format) |
| Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Pituitary gland. |
| Post translational modification | N/A |
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Length | 327 Amino acids |
| Molecular weight | 37684 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1324422 2 PubMed abstract 1328228 3 Clay C.M., Nelson S.E., Campion C.E., Digregorio G.B.; Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P13562 Detail in HMRbase Q99NF2 Detail in HMRbase |
| Gene ID | 14715 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |