A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21061 |
| Swiss-prot Accession number | P97639 (Sequence in FASTA format) |
| Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1) (Fragment). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | High level in the brain, moderate amounts in the eye and skeletal muscle, and small amounts in tongue and pituitary. |
| Post translational modification | N/A |
| Function | Receptor for melanin-concentrating hormone, coupled to G proteins that inhibit adenylyl cyclase. |
| Protein Length | 360 Amino acids |
| Molecular weight | 39728 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 9531978 2 PubMed abstract 8977118 3 PubMed abstract 10559938 4 PubMed abstract 10421368 |
| Hormone | P14200 Detail in HMRbase |
| Gene ID | 83567 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |