A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21036 |
| Swiss-prot Accession number | P35346 (Sequence in FASTA format) |
| Description | Somatostatin receptor type 5 (SS5R). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. |
| Post translational modification | N/A |
| Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
| Protein Length | 364 Amino acids |
| Molecular weight | 39202 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7908405 2 PubMed abstract 8373420 3 PubMed abstract 8078491 4 PubMed abstract 11157797 5 PubMed abstract 15616553 6 PubMed abstract 7908405 7 PubMed abstract 8373420 8 PubMed abstract 8078491 9 PubMed abstract 11157797 10 PubMed abstract 15616553 |
| Hormone | P61278 Detail in HMRbase |
| Gene ID | 6755 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |