A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21024 |
| Swiss-prot Accession number | P32214 (Sequence in FASTA format) |
| Description | Calcitonin receptor precursor (CT-R) (C1A/C1B). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. |
| Protein Length | 516 Amino acids |
| Molecular weight | 60292 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 8391477 2 PubMed abstract 8395656 3 PubMed abstract 8391477 4 PubMed abstract 8395656 |
| Hormone | P01257 Detail in HMRbase |
| Gene ID | 116506 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |