A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20974 |
| Swiss-prot Accession number | O42602 (Sequence in FASTA format) |
| Description | Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1)(Corticotropin-releasing hormone receptor 1) (CRH-R 1). |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a receptor for corticotropin releasing factor. Shows high-affinity binding for urotensin I. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). |
| Protein Length | 415 Amino acids |
| Molecular weight | 47786 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 9326293 |
| Hormone | P49188 Detail in HMRbase |
| Gene ID | 373580 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |