A database of hormones and their receptors
Receptor

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HMRbase accession number20957
Swiss-prot Accession numberP43219 (Sequence in FASTA format)
DescriptionGastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor).
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationCell membrane; Multi-pass membrane protein
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 2 family.
Tissue SpecificityPresent in the pancreas as well as the gut, adipose tissue, heart, pituitary, and inner layers of the adrenal cortex, whereas it is not found in kidney, spleen, or liver. It is also expressed in several brain regions, including the cerebral cortex, hippocampus, and olfactory bulb.
Post translational modificationN/A
Function This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Length455 Amino acids
Molecular weight52257
Domain Name7tm_2  HRM  
References1  PubMed abstract 8243312
HormoneN/A
Gene ID25024      
PDB IDN/A
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated