A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20849 |
| Swiss-prot Accession number | Q8JG70 (Sequence in FASTA format) |
| Description | Alpha-2Da adrenergic receptor (Alpha-2Da adrenoceptor) (Alpha-2Daadrenoreceptor) (Alpha(2Da)AR). |
| Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine > oxymetazoline. |
| Protein Length | 408 Amino acids |
| Molecular weight | 46199 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |