| HMRbase accession number | 20837 |
| Swiss-prot Accession number | Q8VBU7 (Sequence in FASTA format) |
| Description | Beta-2 adrenergic receptor (Adrenergic receptor, beta 2). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
| Protein Length | 418 Amino acids |
| Molecular weight | 46960 |
| Domain Name | 7tm_1 |
| References | 1 Pravenec M., Zidek V., Kostka V., Mlejnek P., Musilova A., Kren V.,Jansa P., Forejt J., Lezin E.S., Kurtz T.W.; "Genetic isolation of a QTL on chromosome 18 associated with saltsensitivity in spontaneously hypertensive rats."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12477932
3 Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
|
| Hormone | N/A |
| Gene ID | 24176 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
A database of hormones and their receptors