A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20822 |
| Swiss-prot Accession number | Q8BH38 (Sequence in FASTA format) |
| Description | Adrenergic receptor, beta 2 (Adult male aorta and vein cDNA, RIKENfull-length enriched library, clone:A530087O16 product:BETA-2ADRENERGIC RECEPTOR, full insert sequence). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
| Protein Length | 418 Amino acids |
| Molecular weight | 46998 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 12477932 2 Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 10349636 4 PubMed abstract 16141072 5 PubMed abstract 16141073 6 PubMed abstract 12466851 7 PubMed abstract 11217851 8 PubMed abstract 11042159 9 PubMed abstract 11076861 10 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 11555 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |