A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20785 |
| Swiss-prot Accession number | P18090 (Sequence in FASTA format) |
| Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
| Protein Length | 466 Amino acids |
| Molecular weight | 50472 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1695899 2 PubMed abstract 2167473 |
| Hormone | N/A |
| Gene ID | 24925 |
| PDB ID | 2FF9 |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |