A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20777 |
| Swiss-prot Accession number | Q9TT96 (Sequence in FASTA format) |
| Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
| Source organism | Bos taurus (Bovine) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
| Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
| Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
| Protein Length | 467 Amino acids |
| Molecular weight | 50137 |
| Domain Name | 7tm_1 |
| References | 1 Ha S.H., Baik M.G., Choi Y.J.; "Cloning of beta adrenergic receptor from Korean cattle."; Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
2 Ha S.H.; "Cloning and characterization of beta adrenergic receptor from Koreannative cattle."; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |