A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20768 |
| Swiss-prot Accession number | P19328 (Sequence in FASTA format) |
| Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
| Protein Length | 453 Amino acids |
| Molecular weight | 50369 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 2158103 2 Schaak S., Cussac D., Paris H.; "Cloning and characterization of the rat alpha2B-adrenergic receptorgene promoter."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7755946 |
| Hormone | N/A |
| Gene ID | 24174 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |