A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20749 |
| Swiss-prot Accession number | O02824 (Sequence in FASTA format) |
| Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
| Source organism | Oryctolagus cuniculus (Rabbit) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Abundant in liver, vas deferens, brain, and aorta, but not in heart. |
| Post translational modification | N/A |
| Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
| Protein Length | 466 Amino acids |
| Molecular weight | 51365 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 9180361 |
| Hormone | N/A |
| Gene ID | 100009237 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |