A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20678 |
| Swiss-prot Accession number | Q9R1W5 (Sequence in FASTA format) |
| Description | Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1receptor) (Calcitonin receptor-like receptor). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | Expressed predominantly in the lung, thymus, heart and brain. |
| Post translational modification | N/A |
| Function | Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). |
| Protein Length | 463 Amino acids |
| Molecular weight | 53265 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 12147211 2 Derst C., Preisig-Mueller R., Gerhardus J., Daut J.; "Cloning and sequencing of mouse CGRP/adrenomedullin receptorsubunits."; Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 10777702 |
| Hormone | N/A |
| Gene ID | 54598 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |