A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20661 |
| Swiss-prot Accession number | P48040 (Sequence in FASTA format) |
| Description | Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor). |
| Source organism | Ovis aries (Sheep) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
| Protein Length | 366 Amino acids |
| Molecular weight | 40401 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7946354 2 PubMed abstract 9194573 |
| Hormone | N/A |
| Gene ID | 443022 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |