A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20434 |
| Swiss-prot Accession number | P70596 (Sequence in FASTA format) |
| Description | Melanocortin receptor 4 (MC4-R). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Brain, enriched in the striatum, nucleus accumbens, and periaqueductal gray. |
| Post translational modification | N/A |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. |
| Protein Length | 332 Amino acids |
| Molecular weight | 36887 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8794897 |
| Hormone | N/A |
| Gene ID | 25635 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |