A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20426 |
| Swiss-prot Accession number | P41968 (Sequence in FASTA format) |
| Description | Melanocortin receptor 3 (MC3-R). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Brain, placental, and gut tissues. |
| Post translational modification | N/A |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
| Protein Length | 360 Amino acids |
| Molecular weight | 40073 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8463333 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 11780052 4 PubMed abstract 15489334 5 PubMed abstract 8463333 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 11780052 8 PubMed abstract 15489334 |
| Hormone | N/A |
| Gene ID | 4159 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |