A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20405 |
| Swiss-prot Accession number | Q7SZL3 (Sequence in FASTA format) |
| Description | 5HT2B serotonin receptor. |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
| Protein Length | 453 Amino acids |
| Molecular weight | 50657 |
| Domain Name | 7tm_1 |
| References | 1 De Lucchini S., Ori M., Nardini M., Marracci S., Nardi I.; "Expression of 5HT-2B and 5HT-2C receptor genes is associated withproliferative regions of Xenopus developing brain and eye."; Mol. Brain Res. 115:192-201(2003).
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| Hormone | N/A |
| Gene ID | 398699 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |