A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20391 |
| Swiss-prot Accession number | Q5ZGX3 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine receptor 1A. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
| Protein Length | 422 Amino acids |
| Molecular weight | 46107 |
| Domain Name | 7tm_1 |
| References | 1 Patra A.K., Saravanan T., Aarthi R., Chugh A.; "Amplification and cloning of serotonin receptor, 5-hydroxy tryptaminereceptor 1A from Indian blood."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
2 Patra S.K.; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 3350 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |