A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20383 |
| Swiss-prot Accession number | Q546Q1 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine4 receptor (5-hydroxytryptamine (Serotonin)receptor 4) (Serotonin receptor 5-HT4). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
| Protein Length | 388 Amino acids |
| Molecular weight | 43761 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 11750916 2 PubMed abstract 12477932 3 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. 4 Syversveen T., Bach T., Kvingedal A.M., Krobert K.A., Kaumann A.J.,Levy F.O.; "Molecular cloning of the human serotonin receptor 5-HT4(b) andpharmacological comparison with the cloned human 5-HT4(a) receptor."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 3360 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |