A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20379 |
| Swiss-prot Accession number | Q4U3W9 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine receptor 2A. |
| Source organism | Mesocricetus auratus (Golden hamster) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
| Protein Length | 471 Amino acids |
| Molecular weight | 52719 |
| Domain Name | 7tm_1 |
| References | 1 Amireault P., Dube F.; "Cloning and sequencing of a golden hamster 5-HT2A receptor cDNA."; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |