A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20359 |
| Swiss-prot Accession number | Q16950 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine 1 receptor (5-HTB1) (Serotonin receptor 1). |
| Source organism | Aplysia californica (California sea hare) |
| Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Reproductive system. |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C. |
| Protein Length | 453 Amino acids |
| Molecular weight | 50622 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7472509 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |