A database of hormones and their receptors
Receptor

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HMRbase accession number20359
Swiss-prot Accession numberQ16950 (Sequence in FASTA format)
Description5-hydroxytryptamine 1 receptor (5-HTB1) (Serotonin receptor 1).
Source organismAplysia californica (California sea hare)
Taxonomical ClassificationEukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia.
Subcellular locationCell membrane; multi-pass membrane protein
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 1 family.
Tissue SpecificityReproductive system.
Post translational modificationN/A
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C.
Protein Length453 Amino acids
Molecular weight50622
Domain Name7tm_1  
References1  PubMed abstract 7472509
HormoneN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated