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HMRbase accession number | 20329 |
Swiss-prot Accession number | P35363 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein. Note=Localizes to the post-synaptic thickening of axo-dendritic synapses |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52842 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1333538 2 PubMed abstract 14988405 |
Hormone | N/A |
Gene ID | 15558 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |