A database of hormones and their receptors
Receptor

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HMRbase accession number20328
Swiss-prot Accession numberP50128 (Sequence in FASTA format)
Description5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2).
Source organismMacaca mulatta (Rhesus macaque)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationCell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity)
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 1 family.
Tissue SpecificityN/A
Post translational modification N/A
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Protein Length471 Amino acids
Molecular weight52603
Domain Name7tm_1  
References1  PubMed abstract 7794950
HormoneN/A
Gene ID613032      
PDB IDN/A
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated