A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20326 |
| Swiss-prot Accession number | P28285 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine receptor 2A (5-HT receptor) (Serotonin receptor2A). |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase. |
| Protein Length | 834 Amino acids |
| Molecular weight | 89521 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1310937 2 PubMed abstract 10731132 3 PubMed abstract 12537572 4 Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15611167 6 PubMed abstract 1310937 7 PubMed abstract 10731132 8 PubMed abstract 12537572 9 Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 15611167 |
| Hormone | N/A |
| Gene ID | 37196 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |