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HMRbase accession number20317
Swiss-prot Accession numberP28566 (Sequence in FASTA format)
Description5-hydroxytryptamine 1E receptor (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31).
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationCell membrane; multi-pass membrane protein
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 1 family.
Tissue SpecificityN/A
Post translational modification N/A
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Protein Length365 Amino acids
Molecular weight41682
Domain Name7tm_1  
References1  PubMed abstract 1608964
2  PubMed abstract 1733778
3  PubMed abstract 1513320
4   Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 14574404
6  PubMed abstract 15489334
7   Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
8  PubMed abstract 10391209
9   Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999).
HormoneN/A
Gene ID3354      
PDB IDN/A
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated