A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20299 |
| Swiss-prot Accession number | P46636 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
| Source organism | Cricetulus griseus (Chinese hamster) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Cricetulus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
| Protein Length | 386 Amino acids |
| Molecular weight | 42896 |
| Domain Name | 7tm_1 |
| References | 1 Wurch T., Palmier C., Colpaert F.C., Pauwels P.J.; "Molecular cloning and expression of a Chinese hamster lung fibroblastcDNA encoding a 5-HT1B receptor."; Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases.
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| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |