HMRbase accession number | 20172 |
Swiss-prot Accession number | A0EQL2 (Sequence in FASTA format) |
Description | Sex hormone-binding globulin precursor (SHBG). |
Source organism | Crocuta crocuta (Spotted hyena) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae;Crocuta. |
Subcellular location | Secreted protein (By similarity). Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis (By similarity) |
Developmental Stage | N/A |
Similarity | Contains 2 laminin G-like domains. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity). |
Protein Length | 393 Amino acids |
Molecular weight | 42443 |
Domain Name | Laminin_G_1 Laminin_G_2 |
References | 1 Miguel-Queralt S., Yalcinkaya T.M., Avvakumov G.V., Place N.,Siiteri P.K., Glickman S.E., Hammond G.L.; "Unusual steroid-binding properties of hyena sex hormone-bindingglobulin."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |