A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20040 |
| Swiss-prot Accession number | Q91ZE5 (Sequence in FASTA format) |
| Description | EGF-like module-containing mucin-like hormone receptor-like 4precursor (EGF-like module-containing mucin-like receptor EMR4)(F4/80-like-receptor) (Seven-span membrane protein FIRE). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 2 EGF-like domains. Contains 1 GPS domain. |
| Tissue Specificity | Predominantly expressed in myeloid cells. |
| Post translational modification | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity). |
| Function | Could mediated the cellular interaction between myeloid cells and B-cells. |
| Protein Length | 689 Amino acids |
| Molecular weight | 77045 |
| Domain Name | 7tm_2 GPS |
| References | 1 PubMed abstract 12023293 2 PubMed abstract 11564768 3 PubMed abstract 16141072 |
| Hormone | N/A |
| Gene ID | 52614 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |