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HMRbase accession number | 11504 |
Swiss-prot Accession number | Q6ZXC3 (Sequence in FASTA format) |
Description | Thyroliberin precursor [Contains: Prothyroliberin; Thyroliberin(Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor)(TRF) (TSH-releasing factor) (Protirelin); Thyroliberin-like]. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the TRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems |
Protein Length | 260 Amino acids |
Molecular weight | 30337 |
References | 1 PubMed abstract 16079264 2 Aoki Y., Masuda T., Yasuo S., Yoshimura T., Ebihara S., Iigo M.,Yanagisawa T.; "Molecular cloning of prepro-thyrotropin-releasing hormone cDNA andits expression in the brain of chicken (Gallus gallus)."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. |
Domain Name | TRH |
Hormone Name | Thyroliberin |
Mature Hormone Sequence | QHP |
Position of mature hormone in Pre-Hormone protein | 3 Residues from position (79-81) |
Receptor | O93603
Detail in HMRbase |
Gene ID | 414344 |
PDB ID | N/A |
Drugpedia | wiki |
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