A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number11404
Swiss-prot Accession numberP12707 (Sequence in FASTA format)
DescriptionInsulin-2 precursor [Contains: Insulin-2 B chain; Insulin-2 A chain].
Source organismXenopus laevis (African clawed frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length106 Amino acids
Molecular weight12207
References1  PubMed abstract 2722842
2  PubMed abstract 2661211
Domain NameInsulin  
Hormone NameInsulin-2 B chain
Mature Hormone SequenceLANQHLCGSHLVEALYLVCGDRGFFYYPKI
Position of mature hormone in Pre-Hormone protein30 Residues from position (24-53)
ReceptorQ9PVZ4    Detail in HMRbase   
Gene ID378695      
PDB IDN/A
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