A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11318 |
| Swiss-prot Accession number | P01240 (Sequence in FASTA format) |
| Description | Prolactin precursor (PRL). |
| Source organism | Ovis aries (Sheep) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the somatotropin/prolactin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Prolactin acts primarily on the mammary gland by promoting lactation, mammogenesis, mitogenesis and osmoregulation |
| Protein Length | 229 Amino acids |
| Molecular weight | 25778 |
| References | 1 PubMed abstract 2911473 2 PubMed abstract 2666265 3 PubMed abstract 7969789 4 PubMed abstract 5497153 5 PubMed abstract 1270193 |
| Domain Name | Hormone_1 |
| Hormone Name | Prolactin |
| Mature Hormone Sequence | TPVCPNGPGNCQVSLRDLFDRAVMVSHYIHNLSSEMFNEFDKRYAQGKGFITMALNSCHTSSLPTPEDKEQAQQTHHEVLMSLILGLLRSWNDPLYHLVTEVRGMKGVPDAILSRAIEIEEENKRLLEGMEMIFGQVIPGAKETEPYPVWSGLPSLQTKDEDARHSAFYNLLHCLRRDSSKIDTYLKLLNCRIIYNNNC |
| Position of mature hormone in Pre-Hormone protein | 199 Residues from position (31-229) |
| Receptor | O46561
Detail in HMRbase |
| Gene ID | 443317 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |