A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11218 |
| Swiss-prot Accession number | P22969 (Sequence in FASTA format) |
| Description | Prorelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain]. |
| Source organism | Equus caballus (Horse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals |
| Protein Length | 182 Amino acids |
| Molecular weight | 20721 |
| References | 1 Min K., Shiota K., Ogawa T.; "Molecular cloning of equine preprorelaxin cDNA."; J. Reprod. Dev. 42:171-178(1996).
2 PubMed abstract 7543295 3 PubMed abstract 2055195 |
| Domain Name | Insulin |
| Hormone Name | Relaxin A chain |
| Mature Hormone Sequence | QLSHKCCYWGCTRKELARQC |
| Position of mature hormone in Pre-Hormone protein | 20 Residues from position (163-182) |
| Receptor | N/A |
| Gene ID | 100033823 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |