A database of hormones and their receptors |
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HMRbase accession number | 11212 |
Swiss-prot Accession number | P51455 (Sequence in FASTA format) |
Description | Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain](Fragment). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | Expressed in the corpus luteum of pregnancy and in the placenta |
Post translational modification | N/A |
Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix |
Protein Length | 166 Amino acids |
Molecular weight | 18761 |
References | 1 PubMed abstract 8182365 2 PubMed abstract 8735594 |
Domain Name | Insulin |
Hormone Name | Relaxin B chain |
Mature Hormone Sequence | DSWMDEVIKLCGRELVRAQIAICGKSTWS |
Position of mature hormone in Pre-Hormone protein | 29 Residues from position (6-34) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |