A database of hormones and their receptors |
|
|
|
|
|
|
HMRbase accession number | 11156 |
Swiss-prot Accession number | P29007 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide precursor (GRP-29) [Contains: Neuromedin-C(GRP-10); C-terminal extension peptide (CTEP)]. |
Source organism | Bombina orientalis (Oriental fire-bellied toad) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Archeobatrachia; Bombinatoridae; Bombina. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the bombesin/neuromedin-B/ranatensin family. |
Tissue Specificity | Brain and stomach. In the stomach GRP was localized, at the base of the gastric pits, to occasional cells whose distribution and appearance were consistent with that of gut neuroendocrine cells |
Post translational modification | N/A |
Function | GRP stimulates gastrin release as well as other gastrointestinal hormones. May have a role as neurotransmitter or neuromodulator |
Protein Length | 155 Amino acids |
Molecular weight | 17813 |
References | 1 PubMed abstract 1551901 |
Domain Name | Bombesin |
Hormone Name | Gastrin-releasing peptide |
Mature Hormone Sequence | SPTSQQHNDAASLSKIYPRGSHWAVGHLM |
Position of mature hormone in Pre-Hormone protein | 29 Residues from position (32-60) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |